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Breaking Research For 6-28-99

 


Vitamin E prevents exercise-induced
DNA damage


 

 

Though this is not a breaking study I feel it needs highlighting because it shows the importance of Vitamin E supplementation in preventing cellular damage induced by exercise.

In a study from Abteilung Medizinische Genetik, Universitat Ulm, Germany, researchers used a single cell gel test to study DNA damage in peripheral white blood cells (WBC) of humans after a single bout of exhaustive exercise and the effect of vitamin supplementation on this damage.

Subjects were asked to run on a treadmill until exhaustion and blood samples were taken before and 24 hours after the run. A clear increase in DNA strand breakage was observed in the 24 hour sample of all probands. A short-term application of multivitamin pills or vitamin E (3 x 800 mg) resulted in a significantly smaller increase of DNA effects in WBC of some probands. When the volunteers were given a supplement of vitamin E (1200 mg daily) for 14 days prior to a run, exercise-induced DNA damage was clearly reduced in all probands. In four out of five subjects, vitamin supplementation completely prevented the induction of DNA damage after exhaustive exercise.

This study revealed that supplementation of vitamin E for 14 days led to a clear increase in vitamin E serum concentrations. Malondialdehyde (MDA), a marker of lipid peroxidation, was measured in the serum of probands in tests with and without vitamin supplementation for 14 days. MDA concentrations were significantly decreased following vitamin E supplementation.

The results demonstrate that vitamin E prevents exercise-induced DNA damage and indicate that DNA breakage occurs in WBC after exhaustive exercise as a consequence of oxidative stress. 

This is just one study showing the revenging effects oxidative stress from exercise causes can be nullified with vitamin E supplementation. I highly recommend taking 800 to 1600 IU's of vitamin E each day.

 

 

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