| A recent Canadian
research study published in the March 10th issue of Neurology revealed a group of patients
with muscular dystrophy and other neuromuscular disorders showed vast improvements in muscle
strength and lean body mass when treated with
creatine monohydrate. Dr. Mark Tarnopolsky and Joan Martin, of McMaster University
Medical Center in Hamilton, Ontario, Canada, treated 81 patients with 10 g of creatine
monohydrate daily for 5 days followed by 5 g daily for 5 to 7 days in an open-label study.
In a second, single-blind study they treated 21 patients with creatine monohydrate.
The researchers measured handgrip, dorsiflexion, knee extensor strength and body weight
before and after treatment.
"Creatine administration increased all measured indices in both studies,"
Dr. Tarnopolsky and Martin report.
"Our data represented the entire group of patients...because we did not find
any subgroup differences in the response for each of the classified groups," the
Canadian researchers note.
Neurology 1999;52:854-857. |